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This study elucidates the non-selective activation mechanism by determining cryo-EM structures of Cagri bound to AMY 1 R-G s and CTR-G s complexes

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Remarkably, the core motifs of CesA_C2 show a relatively high homology to the second C domain in Vlm1 of the valinomycin NRPS although the overall similarities between the two NRPS is low (approx

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