Although vitamin C has an overall low toxicity risk in healthy individuals, consuming too much of it can cause some adverse gastrointestinal side effects, including cramps, nausea, and diarrhea (11, Additionally, since a high vitamin C intake increases the bodys absorption of non-heme iron, consuming too much vitamin C could cause problems for people with hemochromatosis, a condition in which the body retains too much iron ( Because of the potential side effects of excessive vitamin C, the IOM has established the following Tolerable Upper Intake Levels (UL) for the vitamin (11): summary To avoid gastrointestinal side effects, keep your vitamin C intake within the ULs established by the IOM
Sources of Vitamin C Vitamin C can be found in various fruits and vegetables, including oranges, strawberries, kiwi, bell peppers, and broccoli
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This results in increased levels of H 2 O 2 in the peroxisome, which can then damage mitochondria, particularly if they have insufficient antioxidant defenses, such as depleted glutathione levels (Walton and Pizzitelli, 2012)
