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Vue MH, Setter SM

Research on mitochondrial-targeted therapies, such as those aimed at maintaining mitochondrial integrity and function, is ongoing, but the majority of these therapies are in early experimental phases with few clinical trials substantiating their effectiveness [47]

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PubMed Research indicates that retinoids including retinol remain the gold standard for topical anti-aging treatments, though their application is frequently limited by skin irritation and poor tolerability, particularly in sensitive or aged populations