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In the phase I dose-escalation portion, subjects were directed to consume 4-oz of grape juice or placebo daily for 2 weeks (weeks 02), 8-oz for 2 weeks (weeks 34), and finally 16-oz daily dose of either treatment (weeks 56)

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The reduction on methemoglobin in erythrocytes of a patient with congenital methemoglobinemia, subjects with erythrocytes glucose-6-phosphate dehydrogenase deficiency, and normal individuals

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