The answer depends on several factors, including the cause and severity of deficiency, your overall health, and how long symptoms have been present
[131] [132] Species from the following genera and the following individual species are known to synthesize B 12 : Propionibacterium shermanii , Pseudomonas denitrificans , Streptomyces griseus , Acetobacterium , Aerobacter , Agrobacterium , Alcaligenes , Azotobacter , Bacillus , Clostridium , Corynebacterium , Flavobacterium , Lactobacillus , Micromonospora , Mycobacterium , Nocardia , Proteus , Rhizobium , Salmonella , Serratia , Streptococcus and Xanthomonas
By tissue type, the application that has the strongest evidence base is soft tissue: muscle strains, ligament sprains, and chronic tendinopathies
Vitamins B1, B6, and B12 are water-soluble, and as such, when absorbed into the body, they are excreted via the kidneys