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The sequences in CXCL10 that bound to IL18R1 in the top two prediction models were the M1 sequence (CLNPESKTI) and the M2 sequence (IGKLEIIPASLSCPRVEIIATMK)

The American Diabetes Association (ADA) guidelines recommend specific GLP-1 agonists with proven cardiovascular benefit (such as liraglutide, injectable semaglutide, and dulaglutide) for patients with type 2 diabetes and established atherosclerotic cardiovascular disease

The method is particularly responsive to chain-breaking antioxidants and can measure scavenging efficiency against a variety of radicals, including peroxyl radicals, hydroxyl radicals, and peroxynitrite

Imaging studies may be warranted based on clinical presentation and risk stratification, following American College of Physicians guidelines (avoiding routine imaging without red flags)