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A study in the New England Journal of Medicine found that among adults who were overweight or obese, those who injected semaglutide weekly lost nearly 15% of their body weight after 68 weeks

In its survey, KFF also found that 56% of GLP-1 users found it difficult to afford the drug, even with health insurance, while 14% said that they had stopped using the medication altogether because of the cost

Even more troubling, research demonstrates that discontinuing GLP-1 receptor agonist treatment leads to significant weight regain, with patients taking liraglutide regaining an average of 2.20 kg and those on semaglutide or tirzepatide regaining 9.69 kg