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The reward circuit and related structures may participate in the interactions between the GLP-1 pathway and psychoactive substances, as GLP-1Rs are expressed in key brain regions like the ventral tegmental area (VTA) and the nucleus accumbens (NAc) that control reward behaviors [54]

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In acquired epilepsies, such as post-traumatic epilepsy following brain injury, the resultant tissue and cellular damage unleashes a pathophysiological cascade promoting ROS production [44,45]

Researchers investigating cellular energy regulation might also explore the potential of 1 amino 5 mq or 5 amino 1 mq peptide for similar metabolic effects