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For example, endogenous fasting levels of ghrelin predict activation of brain regions involved in reward processing in response to pictures of highly caloric and palatable food, including the caudate, amygdala, anterior cingulate, hippocampus, insula, and orbitofrontal cortex (OFC) [22,23]

Leaky gut contributes to systemic inflammation affecting brain, heart, and other tissues, driving chronic illness

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