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(1977b)

Third, the APR-017 and LCS3 induced increase in ROS, decrease in GSH, and inhibition of cell growth in VRK2-KO cells could be reversed by supplying a GSH compensator

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Neuronal Slc25a39 knockout abolished FGF21-mediated protection against brain edema, lesion volume, and neurological deficits following TBI in mice Consistent with previous findings, the protective effects of FGF21 on lesion volume post-TBI were evident in Slc25a39 fl/fl mice but absent in Slc25a39 CKO mice