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[PUBMED Abstract] Long GV, Luke JJ, Khattak MA, et al.: Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, randomised, phase 3 trial

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Temporary dose reductions during particularly symptomatic periods, followed by re-escalation once symptoms stabilize, represents a common clinical approach