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Patients may need a more careful discussion if they have a history of: Previous NAION in one eye Significant optic nerve crowding Diabetes with vascular complications Sleep apnea, especially untreated sleep apnea High blood pressure or low nighttime blood pressure Cardiovascular disease Sudden unexplained vision loss in the past This does not automatically mean a GLP-1 medication is unsafe, but it does mean the patient should have a personalized risk-benefit discussion with their medical provider

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In general, in could take up to five weeks for your body to remove semaglutide from your system

Glycemic Control and Cardiovascular Health: Improved glycemic control is crucial for individuals with diabetes to reduce the risk of cardiovascular complications