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The compounds safety and pharmacological profile have been comprehensively assessed in rodent models.In preclinical trials, including those involving ovariectomized (OVX) rat models, both low- and high-dose AOD-9604 regimens showed no significant toxicity

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It has healed cutaneous wounds in the colon, stomach, esophagus, and small intestine.37,38 It has also healed deep tissue wounds and fistulas in rodents.39,40 Chemical burns can be particularly challenging to treat due to the nature of the injuries they cause, and there are no optimal therapies for them

SREBP-1-mediated lipogenesis confers resistance to ferroptosis and improves endothelial injury