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(High dosages of IV-administered glutathione can overload our kidneys.) The Philippine Food and Drug Administration (FDA), meanwhile, also noted that injectable glutathione isnt approved for the purpose of skin lighteningits only allowed for use as part of chemotherapy treatments

As a strong antioxidant, topical glutathione helps to: neutralize free radicals

Since L-cysteine is the rate-limiting amino acid in glutathione synthesis, an NAC supplement is a bioavailable cysteine donor that can increase cellular glutathione levels

Studies comparing routes consistently show IV glutathione produces five to ten times higher peak plasma concentrations than oral dosing (PubMed PMID: 24791752)