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We next asked whether reactive oxygen species (ROS) or subsequent NRF2 induction caused by GSH depletion could impact SLC25A39 levels

4.4 Interactions between cartilage and synovium 4.4.1 Interplay between cytokines released by chondrocytes and synovial cells When cartilage is damaged, chondrocytes release proteoglycan fragments, type II collagen fragments, and diverse injury-associated factors that synovial cell surface pattern recognition receptors (PRRs) can detect, prompting synovial hyperplasia and proinflammatory cytokine secretion (139)

Whitening effect 2. Wrinkle improvement 3. Antioxidant