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KumanyikaSKObarzanekEStettlerNBellRFieldAEFortmannSPet al

The platform asked about a list of higher-risk conditions and contraindications, including pancreatitis, pancreatic cancer, insulin-dependent diabetes, hypoglycemia, medullary thyroid cancer history, MEN-2, liver failure or cirrhosis, chronic kidney disease, gallstones, recent gastric bypass, and thyroid issues

In contrast, its paralog CHAC2 remains unresponsive, highlighting CHAC1s unique role in stress adaptation (Ward et al., 2024)

The resulting buildup of iron damages mitochondria, causing the cerebellum, cardiomyocytes, and dorsal root ganglia to malfunction