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Otherwise healthy until they werent

168 Indeed, liver biopsies confirm that the prevalence of clinically significant fibrosis in MASLD and MASH patients is only 20.27% and 35.14%, respectively, 169 with lower proportions in patients with normal or lean body weight, 170 suggesting that antifibrotic treatment may not be necessary for a larger proportion of patients

However, a 2024 study analyzing global pharmacovigilance data found a higher-than-expected number of suicidal ideation reports among semaglutide users compared to other diabetes medications

Near-term cost driver: Prescription drug trend can rise several percentage points for plans that cover GLP-1s