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A 2025 Phase I trial (Lee & Burgess, 2025) demonstrated that IV BPC-157 doses up to 20 mg were tolerated in healthy volunteers with no serious adverse events

Enhanced fat metabolism The claim that b12 enhances fat metabolism during weight loss oversimplifies b12's metabolic roles

It is also used to manage vitamin B12 deficiencies resulting from specific surgeries, diseases of the stomach or gut, and any other genetic disorders affecting vitamin B12 metabolism

In his worst-case scenario to date, one patient, who he described as a young "fit" man, developed early insulin resistance from a growth hormone-stimulating peptide that had him charting a course toward early diabetes