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In fact, CVOTs are designed to maintain glycemic equipoise, allowing for therapeutic augmentation to achieve desired blood sugar outcomes between the investigational therapy and placebo

Stabilizing thyroid function with appropriate medication (typically levothyroxine) must come first before addressing weight loss through additional therapies

The approval of oral semaglutide expanded the range of medically supported weight loss therapies by introducing a non-injectable GLP-1 option

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