Second, the MGBA is bidirectional and the gut highly modulates, as much as the brain influences, state of gut physiology
One could speculate that a key treatment strategy for progressive MS could involve targeting CNS-resident B cells, not aiming to suppress their traditional immunological (mis)behavior, but instead to quell a yet-to-be-discovered unconventional action, possibly related to secretion of an MS-specific myelin toxin into the CSF
NAD+ and glutathione naturally decline with age , contributing to cellular dysfunction, oxidative stress, and increased risk of chronic diseases like Alzheimer's, Parkinson's, and metabolic disorders
Furthermore, these vitamins can work synergistically to enhance AD treatment