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Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome

Brenner added, this also meant the mice could not develop any autoimmune disease such as multiple sclerosis. Further tests confirmed that the mice cannot produce any GSH in their T cells, and indicated that several signaling events that directly boost metabolism and increase energy consumption are lacking

However, scientists dont yet understand how or why

J Med Chem 48(22):69706979 Rydberg P, Gloriam DE, Zaretzki J et al (2010) SMARTCyp: a 2D method for prediction of cytochrome P450-mediated drug metabolism