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6.3.1 Carvacol An investigation is carried out using a colitis model induced with A.A to evaluate the antioxidant and anti-inflammatory efficacy of a phenolic monoterpene, carvacol revealed that pretreatment with carvacol showed decreased level of inflammatory mediators, DAI, macroscopic and microscopic damages and also significant elevation of antioxidant enzymes in the colon tissue [107]

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Safety (GRAS status) plus clinical study success An initial published animal study demonstrated Glyteine to be safe with no observed side effects at the high daily dose of 1 g/kg body weight for 90 days