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Fish and mammalian metallothioneins: a comparative study

Furthermore, despite several studies providing interesting data, this association should be interpreted with caution because the majority of these studies did not report or adjusted for the effect of ITB in their survival analyses [24]

It was suggested that the salt bridge between E124 3.33 and R283 6.55 (superscripts represent BallesterosWeinstein numbering 36 ) of GHSR divides the ghrelin-binding pocket into two cavities, cavity I and II, and the octanoyl moiety of ghrelin was predicted to occupy a hydrophobic crevasse between TM6 and TM7 in the large cavity I 34

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