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In general, repeated cycles of weight loss and regain is associated with worsened cardiometabolic risk factors, says Sara Velayati, MD, obesity medicine specialist and assistant professor at Albert Einstein College of Medicine in New York City

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Unfortunately, they also make long-term weight loss extremely difficult and are a major reason people experience weight regain after dieting

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FcRn is broadly expressed across a range of hematopoietic and non-hematopoietic cells 37,38,39,40 , including endothelial cells, where it is predominantly localized within intracellular endosomal compartments 41,42,43,44,45,46,47,48,49

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