10.1371/journal.pone.0035823 Summary Keywords clinical applications, glycyrrhizin, glycyrrhizin preparations, liver disease, pharmacological mechanisms, safety Citation Ma T, Hao H, Wang S, Qiu D, Cao W, Deng W, Wang S, Li X, Zhang Z, Wei X, Yao L, Gao Z, Yi W, Liu R and Li M (2026) Glycyrrhizin preparations in liver diseases: a narrative review of mechanisms and therapeutic potential
PTP-1B, phosphotyrosine phosphatase 1B
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It stimulates lipolysis (breakdown of stored fats) and inhibits lipogenesis (formation of new fat), primarily via activation of -adrenergic and AMP-activated protein kinase (AMPK) pathways