can you exercise while on semaglutide and Exercise: How to Work Out Safely Exercise on Semaglutide: Safe Workouts

Trial design: 751 adults with obesity (BMI 30, or 27 with at least one comorbidity) No type 2 diabetes 72-week follow-up Tirzepatide 10mg or 15mg vs Semaglutide 2.4mg Results at 72 weeks: When looking at tirzepatide weight loss results from SURMOUNT-5 alongside semaglutide weight loss results from the STEP trials, the gap is consistent and statistically significant across every subgroup sex, age, baseline BMI, and presence of metabolic comorbidities

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Small human trials

IGF1-LR3 has a much longer half-life, reported around 20 to 30 hours, so a single daily dose stays active across the day and needs fewer injections