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Furthermore, RyR proteins contain a significant quantity of sulfhydryl groups in comparison with the other contractile proteins, and this supports the hypothesis that modulation of RyR and release of mediated NO can help increase muscle contraction following the consumption

Given the documented risks associated with high-dose or long-term use of flavonoids, including hepatotoxicity, genotoxicity, endocrine disruption, gut microbiota dysbiosis, and drug interactions, it is imperative to develop optimized oral and topical delivery strategies

According to the World Health Organization, nearly 75 million people suffer from alcohol-related conditions, with ~3 million deaths annually attributed to alcohol consumption [3]

The following antibodies were used: anti-Nrf2 (monoclonal, 1:1000, Santa Cruz)