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Clinical evidence for weight loss in nutrient-replete individuals is limited

The body uses B12 slowly over time, with excess amounts stored for future use, allowing the vitamin to remain in the body for weeks or even months

NNMT methylates nicotinamide (a form of vitamin B3) using S-adenosylmethionine (SAM) as the methyl donor

This may include: a specialist in treating blood conditions (a haematologist) if you have vitamin B12 or folate deficiency anaemia and your GP is uncertain of the cause, you're pregnant or symptoms suggest your nervous system has been affected a specialist in conditions that affect the digestive system (a gastroenterologist) if your GP suspects you do not have enough vitamin B12 or folate because your digestive system is not absorbing it properly a specialist in nutrition (a dietitian) if your GP suspects you have a vitamin B12 or folate deficiency caused by a poor diet A dietitian can devise a personalised eating plan for you to increase the amount of vitamin B12 or folate in your diet