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Cell Chem Biol 29(11):1588-1600.e7 Buratta S et al (2020) Lysosomal exocytosis, exosome release and secretory autophagy: the autophagic- and endo-lysosomal systems go extracellular

Poison Centers have seen a nearly 1,500% increase in calls since 2019 related to overdose or side effects of injectable weight-loss drugs

In 2014, Novo Nordisks Saxenda (liraglutide, first approved in diabetes medication Victoza) was approved for chronic weight management for obese and overweight adults

Reductions in these markers have been observed with other GLP-1 receptor agonists, largely attributed to weight loss rather than a confirmed direct drug effect