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Interestingly, several cross-sectional case-control studies have reported that patients with AD from various countries exhibit lower UA levels compared to healthy individuals [109, 110]

reported that the majority of the Gypsy Narikuravar population in Puducherry demonstrate poor awareness of oral health and hygiene, lacking knowledge of basic practices such as appropriate tooth brushing techniques, the use of toothpaste, and other essential oral hygiene aids (219)

In clinical practice, a B1-B6-B12 injection may be considered when oral therapy is insufficient or not feasible, such as in malabsorption, severe deficiency, or when accelerated replenishment is desired under medical supervision

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