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Besides, it is important to consider that intestinal GLP-1 has a local concentration in the nM range (10100 pico moles per gram of tissue, see Figure 1), further advocating that the main action of this protein have evolved to be locally restricted

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fcHF-fed rats had similar caloric intake, body weight, adiposity, and plasma leptin concentrations as rats on the fcHS diet ( MTII inhibited all dietary components in rats on CHOW, fcHS, fcHF, and fcHFHS diet, although sugar intake was less inhibited compared to chow and saturated fat

The analysis included 281,656 people