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Guinea pigs (Hartley, both sexes, 500-700 g b.w.) with whole body plethysmography, urethane anesthesia (1.5 g/kg i.p.), artificial ventilation under constant pressure (0.98 kPa), and relaxation of skeleton musculature by suxamethonium (0.2 mg/kg i.v.) were used in the present experiments

Regulatory watch Last reviewed Jul 12, 2026 Next review Jul 24, 2026 Evidence snapshot Human trial record: a Phase 1 safety and pharmacokinetics registry entry has no posted efficacy result

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