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Some also negatively impact the immune defense system, allowing pathogens to settle down or aggravate existing bacterial or viral parasitic diseases

Wayne (NJ): Bayer HealthCare Pharmaceuticals Inc, 2009 Dern RJ, Beutler E, Alving AS

simultaneously, it elicits secondary ER-agonist effects in bone, preventing osteoporosis, but also acts as an agonist in the uterus, leading to an increased risk of endometrial cancer (Rachner et al., 2018