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Practical takeaway: On hot days, hydrate proactively before drinking begins, not just in reaction to feeling thirsty

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[4] [22] Serious but rare adverse effects require immediate medical attention and include: Pancreatitis : Severe abdominal pain radiating to the back, with or without vomiting Gallbladder disease : Right upper quadrant pain, particularly after meals Acute kidney injury : Usually secondary to severe dehydration from gastrointestinal symptoms Severe allergic reactions : Rash, difficulty breathing, or swelling of face, lips, or throat Patients should contact their healthcare provider if they experience persistent vomiting, severe abdominal pain, signs of dehydration, or any concerning symptoms

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