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In 1933, phlorizin was found to completely inhibit renal glucose reabsorption, highlighting its potential to regulate blood glucose

In contrast with the mouse and hamster, the rat, guinea pig and man are susceptible to the hepatotoxic effects of AFB 1 [34]

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However, the molecular pathways and intracellular signaling cascades involved in the inhibition of cancer are very broad and complex, and there is a clear need for further studies