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They can also improve how your body regulates blood sugar and processes energy, which has benefits for your overall health

Biol Psychiatry (2013) 74:1525.10.1016/j.biopsych.2013.01.007 197 MunkholmKBraunerJVKessingLVVinbergM

Important gene mutation types in monogenic obesity PATHOGENIC MECHANISMS AND CLINICAL MANIFESTATIONS OF MC4R -DEFICIENT OBESITY Numerous genetic screening studies in cohorts with severe early-onset obesity have confirmed that obesity due to MC4R deficiency is currently the most common cause of monogenic obesity, highlighting the critical role of MC4R in energy balance regulation [21-24]