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Direct glutathione supplementation: An RCT in India randomized 206 people with type 2 diabetes (aged 31-78, HbA1c 7.1-9.7%) to receive either 500 mg glutathione daily alongside antidiabetic medications for 6 months, or antidiabetic medications alone

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The expression of EAAT2 in PD animal models has been studied, and the down-regulation of EAAT2 has been found in both 6-hydroxydopamine and acute 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine models in the mouse striatum (Holmer et al., 2005

Diarrhoea: The Glutathione infusion impacts the gut microbiome, leading to increased bowel movements or loose stools