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Abstract: Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly prescribed for obesity and type 2 diabetes, resulting in rapid or massive weight loss (MWL) that can profoundly affect facial adipose tissue (AT) and skin homeostasis

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Decreased Appetite is expected but continuous excessive exercise and starvation should be avoided.Dehydration is of concern since again it can cause hypotension,renal failure ,fainting and more issues

Benefits may include reduced appetite, improved metabolism, and gradual, sustainable weight loss similar to the results seen with brand-name versions