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Patients should avoid IGF-1 LR3 without medical clearance if they have blood sugar problems, diabetes risk, cancer history, abnormal growth concerns, cardiovascular disease, kidney or liver issues, active illness, pregnancy, breastfeeding, or current prescription medication use

They extend the anagen (growth) phase of the hair cycle, strengthen hair follicles, and improve scalp circulation

Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake

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