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Numerous studies indicate that polyphenols including hydroxycinnamic acids (caffeic acid and curcumin), flavanols (quercetin, catechin, and epigallocatechin gallate), flavanones (hesperetin), isoflavones (genistein), anthocyanidins (cyanidin and procyanidin), and stilbenes (resveratrol), mainly in fresh fruit and vegetables, perform their anticarcinogenic mechanism through the upregulation of tumor suppressors and autophagy by modulating some metabolic signaling pathways, thus reducing the risk of HCC [48,49]

However, these are the most severe tears and usually require surgical treatment to restore knee function

Her urine-organic acid analysis indicated an increase in 5-oxoproline levels, although the difference was not statistically significant compared with that of previously observed values