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Some studies have shown reduced expression of major components of the electron transport chain in the striatum, frontal cortex, and substantia nigra of PD patients (43)

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In support of a role for DHA in preventing adverse statin effects, cultured mouse hepatocytes exposed to statin (10 M simvastatin for 24 hr) had reduced viability that could be prevented by the addition of DHA, but not addition of saturated or monounsaturated fatty acids (Fig