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While insulin and IGF-1 share structural similarities and activate overlapping intracellular signaling pathways, such as the PI3K/Akt and MAPK pathways, they exhibit differential localization within the brain, which may impact their distinct roles in neuronal function and mood regulation [94, 95]

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Effects of L-arginine plus vitamin C supplementation on l-arginine metabolism in adults with long COVID: secondary analysis of a randomized clinical trial

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