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The thermic effect of proteinthe energy required to digest and metabolize itis approximately 20-30% of calories consumed, compared to 5-10% for carbohydrates and 0-3% for fats, according to metabolic studies

Additionally, tirzepatide suppresses glucagon secretion, slows gastric emptying, and promotes satiety through central nervous system pathways, leading to reduced caloric intake and weight loss

~30 days after last dose

Clinical trials are now needed to confirm these protective effects in patients and explore whether GLP-1 receptor agonists can slow, or even halt, the progression of this vision-robbing condition.