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To accomplish this, a wide range of cell types are arranged in the intricate three-dimensional structure of the nephron, the functional unit of the kidney, enabling it to react with various intracellular and intercellular signals, as well as hormonal, neurological, and inflammatory stimuli (10)

Hirata and colleagues demonstrated that exendin-4 attenuated high-salt load induced hypertension, prevented angiotensin II induced hypertension and inhibited angiotensin II-induced phosphorylation of ERK1/2 [128]

Robaczewska, J