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After 4 weeks of oral administration of 5amino1mq tablets (510 mg/kg) to aged mice (1820 months old), muscle mass was significantly increased, grip strength was enhanced by approximately 40% compared with the control group, and muscle endurance and exercise capacity were also notably improved.Further studies revealed that 5amino1mq inhibits excessive NNMT activation in muscle tissue, restores NAD levels, activates the SIRT1 pathway, reduces muscle protein degradation, and promotes muscle protein synthesis, thereby maintaining muscle mass
Ningn suplemento sirve si la dieta es deficiente
doi: 10.3389/fnut.2023.1304209 Received 29 September 2023 Accepted 13 December 2023 Published 05 January 2024 Volume 10 - 2023 Edited by Mahban Rahimifard, Tehran University of Medical Sciences, Iran Reviewed by Shayne Mason, North-West University, South Africa
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