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10.1073/pnas.92.6.1989 93 ServilloL.D'OnofrioN.CasaleR.CautelaD.GiovaneA.CastaldoD.et al (2017b)

It promotes angiogenesis (the growth of new blood vessels needed for healing), accelerates tendon-to-bone and Achilles repair, and reduces inflammation, partly by activating the FAK-paxillin cell-migration pathway and upregulating growth-hormone receptors in tendon cells (Molecules, 2014

Potential for Mood Improvement : Some studies indicate that isotretinoin treatment can lead to improvements in mood and anxiety, possibly due to the alleviation of acne-related psychological distress

The "clumping" paper he cited (PMC5665799) studies peptides that are 29 amino acids or longer and form structured fibrils through specific mechanisms involving hydrophobic regions and beta-sheet formation