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Importantly, melanocytes stimulated by cytokines express surface proteins such as CD40 and ICAM1 in addition to MHC class II, allowing for co-stimulation of T cells

Indirectly, ROS clearance is facilitated through the inhibition of the NF-B pathway, which consequently downregulates the expression of inflammatory mediators and cytokines, such as tumor necrosis factor-alpha (TNF-) and interleukin-8 (IL-8)

Mol Pharm 10:23402349 Mata-Marin JA, Mendez-Cruz R, Arroyo-Anduiza CI, Mata-Marin LA, Gaytan-Martinez J, Asbun-Bojalil J (2013) Effect of antiretroviral therapy on inflammatory markers of endothelial dysfunction in HIV treatment-naive infected patients

*Correspondence: Ziming Ma, [email protected]