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Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response

10.1007/s00210-025-04436-w 91 LiF.LiuT.ZhangQ.WangW.MaX.MaR.et al (2026)

Over the long term, our expectation is that this will be cost neutral. The drug costs will gradually be lowered under the plan

In some embodiments, the auris-acceptable penetration enhancer is a surfactant comprising an alkyl-glycoside wherein the alkyl-glycoside comprises a sugar linked to a hydrophobic alkyl (e.g., an alkyl comprising about 6 to about 25 carbon atoms) by an amide linkage, an amine linkage, a carbamate linkage, an ether linkage, a thioether linkage, an ester linkage, a thioester linkage, a glycosidic linkage, a thioglycosidic linkage, and/or a ureide linkage