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Increased irregularities in blood flow patterns result in elevated levels of disturbed shear stress [12]

Given that immune cell accumulation plays a vital role in eye diseases pathogenesis, previous researchers have also studied the effect of GLP-1RAs on macrophages and discovered that it could reduce macrophage infiltration in addition to altering macrophage phenotypes in multiple sclerosis and nephropathy (Chiou et al., 2019

Although IL-24targeting agents have not yet been developed for clinical use, our data provide a proof-of-concept basis for considering neutralizing strategies

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