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Esto causa gran variedad de signos y sntomas neurolgicos, incluyendo parestesias de manos y pies, disminucin de la sensacin de vibracin y posicin con la consiguiente prdida del equilibrio, disminucin de reflejos tendinosos profundos y en etapas posteriores prdida de la memoria, confusin, depresin, delirio, alucinaciones, psicosis franca y hasta prdida de la visin central

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As a result, new skin growth is firm and tight, allowing it to resist unwanted changes such as creasing and wrinkling

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